Animal Care & Ethics

As a leading CRO, our responsibility is to manage your regulatory test requirements under GLP, while maintaining the highest level of animal welfare practices.

In recent times, advances in health and food technology have played a vital role in enhancing the health of the human race and society. Due to ever-changing needs and urge, establishment of new molecules and techniques to cure diseases and improve food production capacity is of paramount importance. This has resulted in a need of animal testing, for establishing safety and risk assessment of molecules.

At JRF Global, animal welfare practices are very important and all the experiments are conducted after approval from the Institutional animal ethics committee (IAEC) . Animal welfare is much more than just a clean and safe environment, and healthy nourishment. JRF follows the best husbandry practices, contributing towards the animal’s enrichment program while ensuring a stress-free and hospitable environment.

JRF Global also follows the 3Rs of humane animal research. The 3Rs are defined as:

• Replacement: Methods that avoid or replace the use of animals.
• Refinement: Improvements to scientific procedures and husbandry that minimise actual or potential pain, suffering, distress or lasting harm, and/or improve animal welfare in situations where the use of animals is unavoidable.
• Reduction: Methods that minimise animal use and enable researchers to obtain comparable levels of information from fewer animals, or to obtain more information from the same number of animals, thereby reducing future use of animals.

The 3Rs form the core of policies and strategy at JRF Global. Therefore, JRF Global offers an ever-expanding range of in vitro genetic toxicology assays, in vitro endocrine disruptor assays, as well as alternative toxicity tests, such as the Local Lymph Node Assay (LLNA), Dermal Absorption, Bovine Corneal Opacity & Permeability Test, Phototoxicity, In vitro Dermal Absorption, Skin corrosion using RhE, Skin Corrosion using Transcutaneous Electrical Resistance (TER) method, Skin corrosion using Membrane barrier test method and In vitro skin irritation - Dermal Irritation in 3D Human Tissue Constructs.

Our Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International accreditation shows our commitment for conducting studies in an ethical and humane manner.

Other JRF policies ensuring quality animal care are:

• All the experiments are conducted in accordance with CPCSEA, (Committee for the Purpose of Control and Supervision of Experiments on Animals) a Governmental body managing ethical animal’s research.
• The uses of small animals are governed through Institutional Animal Ethic Care (IAEC)
• The use of large animals is governed through CPCSEA after recommendation from IAEC
• Accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International
• A team of veterinarians is appointed as Institutional Animals Welfare Officers, to ensure compliance of Institutional Animal Welfare policies.